Ovarian Cancer Treatment in Istanbul: Expert Gynecologic Oncology
Istanbul's JCI-accredited gynecologic oncology centers offer comprehensive ovarian cancer treatment — from cytoreductive surgery and carboplatin-paclitaxel chemotherapy to PARP inhibitors and HIPEC — at 60-75% lower cost than the UK, following ESMO and NCCN guidelines.
How much does ovarian cancer treatment cost in Istanbul?
Cytoreductive surgery costs $10,000–$20,000 in Istanbul versus £25,000–£50,000 in the UK. Carboplatin-paclitaxel (6 cycles) costs $8,000–$15,000 versus £20,000–£40,000. Olaparib maintenance costs $3,000–$5,000/month versus £8,000–£12,000/month. Total treatment cost for stage III ovarian cancer is typically $25,000–$50,000 in Istanbul versus £60,000–£120,000 in the UK.
Cytoreductive surgery: primary and interval debulking
The goal of cytoreductive surgery is to remove as much tumor as possible. Istanbul's gynecologic oncologists perform primary debulking surgery (before chemotherapy) and interval debulking surgery (after neoadjuvant chemotherapy). Optimal debulking — leaving no visible residual disease — is associated with significantly better survival.
Chemotherapy: carboplatin-paclitaxel and bevacizumab
The standard first-line chemotherapy for ovarian cancer is carboplatin-paclitaxel (6 cycles, every 3 weeks). Bevacizumab (Avastin) is added for high-risk patients. For platinum-resistant relapse, Istanbul centers offer pegylated liposomal doxorubicin, gemcitabine, and topotecan.
PARP inhibitors for BRCA-mutated ovarian cancer
BRCA1/2 testing is performed for all ovarian cancer patients in Istanbul. BRCA-mutated patients are eligible for PARP inhibitor maintenance therapy after platinum-based chemotherapy. Olaparib reduces the risk of relapse by 70% in BRCA-mutated patients. Istanbul centers offer olaparib, niraparib, and rucaparib at 60-65% lower cost than the UK.
How to start ovarian cancer treatment in Istanbul
Send your pathology report, CT scan, CA-125 and HE4 tumor markers, and BRCA testing results to our coordination team. Istanbul's gynecologic oncology tumor board will review your case and provide a treatment plan within 48-72 hours.
